GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2243480 | 1 | rs7778911 | chr7:65694506 | CCT6P1 | chr7:65216092-65228661:+ | -0.64 | -5.29 | 7.77E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs778679 | chr7:65840911 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs778691 | chr7:65873092 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs778704 | chr7:65863467 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs7787230 | chr7:65629099 | CCT6P1 | chr7:65216092-65228661:+ | -0.65 | -5.41 | 4.64E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs778729 | chr7:65824419 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Diabetic kidney disease |
| THYM | cis | rs6545883 | 1 | rs778758 | chr2:61782161 | AHSA2 | chr2:61404553-61414058:+ | -0.46 | -5.79 | 9.05E-8 | Tuberculosis |
| THYM | cis | rs6545883 | 1 | rs778758 | chr2:61782161 | C2orf74 | chr2:61372243-61391964:+ | 0.58 | 7.47 | 3.96E-11 | Tuberculosis |
| THYM | cis | rs6545883 | 1 | rs778762 | chr2:61782921 | AHSA2 | chr2:61404553-61414058:+ | -0.43 | -5.3 | 7.63E-7 | Tuberculosis |
| THYM | cis | rs6545883 | 1 | rs778762 | chr2:61782921 | C2orf74 | chr2:61372243-61391964:+ | 0.58 | 7.45 | 4.23E-11 | Tuberculosis |
| THYM | cis | rs6545883 | 1 | rs778763 | chr2:61785639 | AHSA2 | chr2:61404553-61414058:+ | -0.43 | -5.3 | 7.63E-7 | Tuberculosis |
| THYM | cis | rs6545883 | 1 | rs778763 | chr2:61785639 | C2orf74 | chr2:61372243-61391964:+ | 0.58 | 7.45 | 4.23E-11 | Tuberculosis |
| THYM | cis | rs6911965 | 1 | rs77902909 | chr6:24478715 | GPLD1 | chr6:24428405-24489850:- | 0.57 | 5.22 | 1.07E-6 | Hematological and biochemical traits |
| THYM | cis | rs2243480 | 1 | rs7792391 | chr7:65773429 | CCT6P1 | chr7:65216092-65228661:+ | -0.64 | -5.29 | 7.77E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs7794661 | chr7:65389730 | CCT6P1 | chr7:65216092-65228661:+ | 0.68 | 4.97 | 3.0E-6 | Diabetic kidney disease |